Dr. V.A. Shiva Ayyadurai delivered the State of the Art Lecture at the 2017 Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics (ASCPT). The theme of the meeting was Advancing Patient Care Through Precision and Translational Medicine. Dr. Shiva's lecture was titled In-Silico Mechanistic Modeling: The Future of Precision Medicine. Dr. Shiva focused on CytoSolve which can be used effectively for in-silico mechanistic modeling, which forms a solid foundation for precision medicine. The event was held on March 15-18, 2017 at Washington Marriott Wardman Park, Washington, DC.